Cephalosporins reaction with dichlorine monoxide

The ene-type chlorination, specific with this halogen atom, of alkenes would account for a somewhat different mode of halogen addition, giving useful allylic chlorides. Efficient and convenient reagents and methods developed are dichlorine monoxide (CI2O equation 36), r-butyl hypochlorite, and electrochemical reactions with chloride ion (equation 37). llie ene-type chlorination proceeds smoothly with 1,1-disubstituted alkenes (74) and (76) to give (75) and (77). Especially, dichlorine monoxide is a potential reagent for complex molecules such as penicillin and cephalosporin derivatives. ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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