Central alveolar hypoventilation syndrome

Specific conditions such as idiopathic central alveolar hypoventilation syndrome (Ondine s curse) or central alveolar hypoventilation syndrome secondary to neurological lesions (trauma, infections, infarction. Shy Drager syndrome) can cause or contrihute to long-term ventilator dependence (40). In most ventilator-dependent patients, however, estimations of respiratory drive indicate that drive is increased and not decreased (18,41-43). 

Nielson DW, Black PG. Mask ventilation in congenital central alveolar hypoventilation syndrome. Pediatr Pulmonol 1990 9 44-45. 

Mobius syndrome in association with congenital central alveolar hypoventilation has been described in Brazil (38). 

Nunes ML, Friedrich MA, Loch LF. Association of misoprostol, Moebius syndrome and congenital central alveolar hypoventilation. Case report. Arq Neuropsiquiatr 1999 57(1) 88-91. 

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