Cellulose genetic mutations

Genetic Mutations, and Chemical Inhibitors of Cellulose Biosynthesis. . 143... 

Much of our understanding of the TCs has, in fact, been obtained from genetic and microscopic analyses. Interestingly, genetic analysis of cellulose-deficient mutants in plants led to the proposal that the rosette TC contains three different nonredundant cellulose synthases, and mutation in any one of these results in a defect in the assembly of cellulose microfibrils (Taylor et al. 2003). In addition, the cellulose synthases identified for cellulose synthesis in the primary cell wall are different from the cellulose synthases required for cellulose synthesis in the secondary cell wall (Robert et al. 2004). In spite of the failure to localize any other protein except the cellulose synthase to the rosette TC, other proteins have been predicted by mutant analysis to be associated with the complex and these may have a direct or indirect role in cellulose synthesis. 

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