Cellobiouronic acid

Avery and Goebel applied this concept to cellobiouronic acid [70], and also to the Sp serotype 3 CPS. Both conjugates to horse semm globuhn were able to induce polysaccharide specific antibodies and remarkably they conferred immunity to challenge by live Streptococcus pneumoniae serotype 3. 

Perhaps, the best support for the theory of restriction to rotation, propounded by Feather and Harris, was provided by an investigation of the hydrolysis of cellobiose (30), cellobiouronic acid (31), and pseudo-cellobiouronic acid (4-0-i8-D-glucopyranosyl-D-glucuronic acid) (32). 

Rate Constants and Activation Energies for the Hydrolysis of Cellobiose, Cellobiouronic Acid, and Pseudocellobiouronic Acid"... 

The stability toward acid hydrolysis of glycosiduronic linkages was referred to earlier. 2-0-(4-0-Methyl-a-n-glucopyranosyluronic acid)-n-xylopyranose (1) is hydrolyzed twenty times slower than 2-0-(4-0-methyl-D-glucopyranosyl)-D-xylitol, and cellobiouronic acid is cleaved at a rate one-thirtieth that of cellobiose. Aldotriouronic acids of type (9) are... 

Polysaccharides isolated from Rhizobium radicicolum and Azotobacter chroococcum cross-react in high dilution in horse anti-Pn III. Part of the structure of the Rhizobium polysaccharide bears a close resemblance to that of Sill, inasmuch as both contain cellobiouronic acid in their respective... 

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