Catalyzed borylation of organic halides

Diborons and HBpin have been found to act as the boron nucleophiles in the presence of a base for the palladium-catalyzed cross-coupling reaction of organic electrophiles. Both reactions provide a simple and direct method for the borylation of organic halides and triflates. 

Br PdCI2(dppf), KOAc, DMSO or DMF, 80°C X = Cl, Br PdCI2(dppf), KOAc, DOSO or dioxane, microwave X = Cl Pd(dba)2-2PCy3, KOAc, dioxane, 80 °C 

X = N2BF4 PdCI2(dppf), MeOH, RT X = N2BF4 Pd(OAc)2-2NHC, THF, RT 

OTf R1, R2, R3 = alkyl PdCI2(PPh3)2-2PPh3, PhOK, toluene or dioxane, 50-80 °C 

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Transition-metal-catalyzed borylation of organic halides with hydrobor-anes 12H(85)1795. 

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