Catalytic asymmetric phase-transfer

In the Park-Jew group s systematic investigation, two types of catalyst - the 1,3-phenyl- and 2,7-naphthyl-based dimeric ammonium salts - were selected as an efficient skeleton of chiral PTCs for the catalytic asymmetric phase-transfer alkylation... 

Catalytic Asymmetric Phase-Transfer Michael Addition to a,f -Unsaturated Esters 119... 

Scheme 6.2 Catalytic asymmetric phase-transfer alkylation of various electrophiles.

Scheme 6.3 Catalytic asymmetric phase-transfer Michael addition and counter anion effects.

Catalytic Asymmetric Phase-Transfer Mannich-Type Reaction... 

Scheme 6.5 Catalytic asymmetric phase-transfer Mannich-type reaction.

For example Shibuguchi, T., Fukuta, Y, Akachi, Y. et al. (2002) Development of new asymmetric two-center catalysts in phase-transfer reactions. Tetrahedron Letters, 45,9539-9543. Ohshima, T., Shibuguchi, T., Fukuta, Y. and Shibasaki, M. (2004) Catalytic asymmetric phase-transfer reactions using tartarate-derived asymmetric two-center organocatalysts. Tetrahedron, 60, 7743-7754. 

ShibasaM M, Ohshima T, Shibuguchi T, Fukuta Y (2004) Catalytic Asymmetric Phase-Transfer Reactions Using Tartrate-Derived Asymmetric Two-Center Organocatalysls. Tetra-hedrrai 60 7743... 

Shibuguchi T, Mihara H, Kuramochi A, Ohshima T, Shibasaki M (2007) Catalytic Asymmetric Phase-Transfer Michael Reaction and Mannich-Type Reaction of Glycine SchiffBases with Tartrate-Derived Diammonium Salts. Chem Asian J 2 794... 

Fukuta Y, Ohshima T, Gnanadesikan V, Shibuguchi T, Nem-oto T, Kisugi T, Okino T, Shibasaki M. Enantioselective syntheses and biological studies of aeruginosin 298-A and its analogs application of catalytic asymmetric phase-transfer reaction. PAAS 2004 101 5433-5438. 

A and its analogues using a catalytic asymmetric phase-transfer reaction and epoxidation. J. Am. Chem. Soc. 2003 125(37) 11206-11207. 

Shibuguchi T, Mihara H, Kuromachi A, Ohshima T, Shibasaki M. Catalytic asymmetric phase-transfer Michael reaction and Mannich-type reaction of glycine Schiff gases with tartrate-derived diammonium Salts. Chem. Asian J. 2007 2(6) 794-801. 

Ohshima T, Shihuguchi T, Fukuta Y, Shihasaki M. Catalytic asymmetric phase-transfer reactions using tartrate-derived asymmetric two-center organocatalysts. Tetrahedron 2004 60 7743-7754. 

Ohshima, T., Gnanadesikan, V., Shibuguchi, T, Fukuta, Y., Nemoto, T., and Shibasaki, M. (2003) Enantioselective syntheses of aeruginosin 298-A and its analogues using a catalytic asymmetric phase-transfer reaction and epoxidation./. Am. Chem. Soc., 125,11206-11207. 

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