Cardiopulmonary resuscitation vasopressin

Wenzel V, Krismer AC, Arntz HR, et al. A comparison of vasopressin and epinephrine for out-of-hospital cardiopulmonary resuscitation. N Engl J... 

In a subgroup analysis of a comparison of vasopressin 40 IU + adrenaline 1 mg (n = 1442) with adrenaline alone (n = 1452) in cardiopulmonary resuscitation, when the initial electrocardiogram showed pulseless activity the rate of survival was higher in those treated with adrenaline alone (5.8% compared with 0%) [46 ]. Overall, 1-year survival was 1.3% versus 2.1% respectively although this was a non-significant difference, it was clear that vasopressin in addition to adrenaline was not beneficial and could be harmful. 

Lae C, Metzger J, Raphael V, Beruben A, Wenzel V, Guinhouya C, Vilhelm C, Marret E. Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation. N Engl J Med 2008 359 21-30. 

Cardiopulmonary resuscitation Epinephrine, vasopressin, and atropine according to ACLS guidelines Identification and treatment of cause including ... 

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