Carboxymethylated gellan

Carboxymethyl gellan gum Metformin HCl lonotropically gelled beads Studies showed ex-vivo bioadhesion of 100% over 24 h and it was observed that carboxymethyl gellan gum beads released metformin at a rate faster than gellan gum. [71]... 

M. Ahuja, S. Singh, and A. Kumar, Evaluation of carboxymethyl gellan gum as a mucoad-hesive polymer, Int. J. Biol. Macromol, 53,114-121, 2013. 

There are several reports on the coating of bone-like hydroxyapatite onto natural polymer substrates. Kawashita et at. [57] reported that carboxymethylated chitin and gellan gum gels, which have carboxyl groups, can form hydroxyapatite on their surfaces in SBF if they are treated with a saturated Ca(OH)2 solution in advance, while curdlan gel, which has no carboxyl group, does not form hydroxyapatite in SBF, even if it is treated with Ca(OH)2 solution. These results support the hypothesis that carboxyl groups induce hydroxyapatite nucleation. Kokubo et at. [58,59] reported that non-woven fabrics of carboxymethylated chitin and alginate fibers also form hydroxyapatite on their surfaces in SBF if they are treated with Ca(OH)2 solution. 

Calcium alginate Calcium carboxymethyl cellulose Calcium glycerophosphate Carrageenan (Chondrus crispus) Carrageenan (Chondrus crispus) extract Furcelleran Gelatin Gellan gum Hydroxypropyl methylcellulose Methyl ethyl cellulose... 

P. Patel, R. Ashwini, S. Shivakumar, B.K. Sridhar. Preparation and evaluation of extended release matrix tablets of diltiazem using blends of tamarind xyloglucan with gellan gum and sodium carboxymethyl cellulose. Pharm Lett. 3 (4) 380-392,2011. 

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