Carboxylic acids trichlorosilane

Titanium dioxide Succinic anhydride Carboxylic acid Trichlorosilane... 

METHYL GROUPS BY REDUCTION OF AROMATIC CARBOXYLIC ACIDS WITH TRICHLOROSILANE-TRI-n-PROPYLAMINE 2-METHYLBIPHENYL... 

Good results may sometimes be achieved with a 4 1 or 5 1 mole ratio of trichlorosilane to carboxylic acid. Excess trichlorosilane is desirable to compensate for losses of this volatile reactant over extended reflux periods. 

Although the exact mechanism is speculative, it has been found that carboxylic acids, but not esters, are reduced directly to the corresponding alcohols on reaction with benzyltriethylammonium borohydride in the presence of trichlorosilane [21]. Yields are generally in excess of 85%. The failure of the system to reduce esters suggests that diborane is not produced during the reaction [22],... 

Carboxylic acid-terminated organosilanes were used in the early studies on chemically bonded glycopeptides to immobilize vancomycin and thiostrepton via then-amino groups, leading to the formation of stable amide bonds between antibiotics and modified silica [7]. In a typical reaction, 4 g of dry silica gel is slurried on 50 mL of dry toluene. Two grams of [l-(carbomethoxy)ethyl]methyldichlorosilane or [2-(carbomethoxy)ethyl]trichlorosilane is dissolved in 15 mL of dry toluene contained in a dropping flask. The organosilane solution is added dropwise over 30 min... 

Herein the focus is on SAMs of trichlorosilanes and thiols. SAMs of carboxylic acids are important as a connection between the LB and self-assembly techniques, but studies of their formation and structure have been relatively limited. SAMs of carboxylic acids on Al203, AgO, and CuO have also been carried out (113—124). 

In choosing a SAM system for surface engineering, there are several options. Silane monolayers on hydroxylated surfaces are an option where transparent or nonconductive systems are needed. However, trichlorosilane compounds are moisture-sensitive and polymerize in solution. The resulting polymers contaminate the monolayer surface, which occasionally has to be cleaned mechanically. Carboxylic acids adsorb on metal oxide, eg, A1 03, AgO through acid—base interactions. These are not specific therefore, it would be impossible to adsorb a carboxylic acid selectively in the presence of, for example, a terminal phosphonic acid group. In many studies SAMs of thiolates on Au(lll) are the system of choice. 

Aromatic carboxylic acids are reduced to benzylic trichlorosilanes. which are cleaved by base to toluenes. It is thus possible to reduce a carboxyl group to a methyl group in two steps.3... 

Thiophen-3-aldehyde has been obtained through the reduction of 3-cyanothiophen with sodium bis-(2-methoxyethoxy)aluminium hydride. This method can hardly compete with the preparation from 3-thienyl-lithium and iVN-dimethylformamide. Nor does the reduction of thio-phen-3-carboxylic acid with trichlorosilane in acetonitrile appear to be of preparative value. ... 

Magnesium hydroxide Succinic anhydride Trichlorosilane Carboxylic acid... 

Aromatic carboxylic acids and esters are reduced to methyl groups in a process in which trichlorosilane, CLSiH, is the reductant. ... 

The reagent titanocene dichloride reduces carboxylic esters in a different manner from that of 10-86, 19-36, or 19-38. The products are the alkane RCH3 and the alcohol R OH. The mechanism probably involves an alkene intermediate. Aromatic acids can be reduced to methylbenzenes by a procedure involving refluxing first with trichlorosilane in MeCN, then with tripropylamine added, and finally with KOH and MeOH (after removal of the MeCN). The following sequence has been suggested ... 

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