Carboxylic acids aldehydes from

Another route to carboxylic acids from aldehyde products (once again, generally produced via hydroformylation catalysis) was discovered by Wakamatsu and coworkers. They reported the carbonylation of aldehydes and primary organic amides to produce A-acylamino acids (equation 16). The reaction is efficiently catalyzed by HCo(CO)4 at 100 °C and 140 bar of 3 2 H2/CO (hydrogen is needed to help stabilize HCo(CO)4). Yields of over 90% of the appropriate... 

Lindgren, B. O., Nilsson, T. Preparation of carboxylic acids from aldehydes (including hydroxylated benzaldehydes) by oxidation with chlorite. Acta Chemica Scandinavica (1947-1973) 1973, 27, 888-890. 

Dondoni, A., Daninos, S., Marra, A., and Formaglio, P, Synthesis of ketosyl and ulosonyl phosphonates by Arbuzov-type glycosidation of thiazolylketol acetates. Tetrahedron, 54, 9859, 1998. Razumov, A.L, and Moskva, V.V., Derivatives of phosphonic and phosphinic acids. Part 26. Synthesis of phosphorylated carboxylic acids from aldehydes and acetals, Zh. Obshch. Khim., 35, 1149, 1965 J. Gen. Chem. USSR (Engl. Transl.), 35, 1151, 1965. 

Carboxylic acids from aldehydes Azlactone synthesis Oxazolones s. 2,654... 

Potassium permanganate Carboxylic acids from aldehydes s. 5,218 KMnOa CHO —>- COOH... 

Benzeneseleninic acidjhydrogen peroxide Carboxylic acids from aldehydes under mild conditions... 

Silver nitrate/sodium hydroxide Carboxylic acids from aldehydes... 

Carboxylic acids may also be prepared by conversion of aldehydes into esters, followed by hydrolysis. See section 109 (Esters from Aldehydes). Some of the methods listed in section 27 (Carboxylic Acids from Ketones) may also be applied to the preparation of carboxylic acids from aldehydes... 

Carboxylic acids from aldehydes cf. 24, 875 also from ketones, acids, esters, and amides, s. S. E. Dinizo et al., Am. Soc. 99,182 (1977)... 

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