Carboxylesterases scavenger function

Maxwell, D.M., Wolfe, A. D., Ashani, Y., Doctor, B.P. (1991). Cholinesterases and carboxylesterases as scavengers for organophosphorus agents. In Cholinesterases Structure, Function, Mechanism, Genetics and Cell Biology (J. Massou-lie, F. Bacon, E. Barnard, A. Chatonnet, B.P. Doctor, D.M. Quinn, eds), pp. 206-9. American Chemical Society, Washington. 

The gut epithelium is the main barrier for metals ingested with food. Efficient detoxifying systems in these cells are of a special importance as they indirectly decide on what kind of genetic material will be successfully transferred to the next generation (Konno and Shishido, 1992). As metals are not detoxified enzymatically they can influence directly or indirectly the functional abilities in some of these systems. Relations between the level of environmental contamination and activity patterns of such enzymes as glutathione 5-transferase, carboxylesterases or enzymes acting as free radical scavengers remain unclear. 

Maxwell DM, Wolfe AD, Ashani Y, Doctor BP. Cholinesterase and carboxylesterase as scavengers for organophosphorus agents. In Massoulie J, Bacou F, Barnard E, Chatonnet A, Doctor B, Quinn DM, eds. Cholinesterases Structure, Function, Mechanism, Genetics, and Cell Biology. Washington, DC American Chemical Society 1991 206-209. 

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