Carborane-functionalized macrocycles

While the synthesis of a variety of single macrocycles containing 1,2- and 1,7-CaBioHio carboranylene linkers has been described, more recent work has focused upon functionalization of the carborane cages from which these hydrophobic species are comprised and the discovery of methods by which such molecules could be made water-soluble. Water solubility would place a hydrophobic cavity bounded by carborane cages in aqueous media and provide a means to support the solubilization of hydrophobic hydrocarbon or carborane-rich structures. Derivatization of B-vertices of carboracycles derived from 1,2- or l.T-CaBioHio carboranylene groups is easily accomplished by well established methods. ... 

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