Carbon double bond reduction

The reductions of alkenes are a special case and are found associated with a,(3-unsaturated carbonyls and not with isolated double bonds. Both norethindrone and 5-fluorouracil have been shown to undergo carbon-carbon double-bond reduction [48—49], as shown in Fig. 14. 

Reduction of carbonyl groups, reduction of alcoholic groups and carbon-carbon double bonds, reduction of nitrogen-containing functional groups, other reductive reactions... 

Reductions are less commonly encountered than are oxidations, yet they constitute a very important group of biotransformations. An example is the reduction of nitro and azo groups. Nitro- and azoreductase enzymes effect these reactions in the liver. Ketones and aldehydes are reducible to secondary and primary alcohols, respectively. On occasion a carbon-carbon double bond reduction is encountered. Table 3-2 summarizes several of these reactions. 

Carbon-carbon double bonds, reduction by lanthanides... 

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