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CAR knock-out mice

5 Another Independently Developed CAR Null Mouse Line [Pg.189]

A variety of GEM models are now available in which aspects of mouse metabolism have been replaced by their human counterparts. Mice with knocked-out mouse pregnane X receptor (mPXR) and knocked-in human PXR (hPXR) have been available for some time. Now, mice with knocked-out mouse constitutive androstane receptor (mCAR) and knocked-in human CAR (hCAR) and mice with both hPXR and hCAR have been generated.63... [Pg.277]

See other pages where CAR knock-out mice is mentioned: [Pg.52]    [Pg.121]    [Pg.124]    [Pg.124]    [Pg.125]    [Pg.127]    [Pg.132]    [Pg.189]    [Pg.189]    [Pg.189]    [Pg.189]    [Pg.192]    [Pg.200]    [Pg.52]    [Pg.121]    [Pg.124]    [Pg.124]    [Pg.125]    [Pg.127]    [Pg.132]    [Pg.189]    [Pg.189]    [Pg.189]    [Pg.189]    [Pg.192]    [Pg.200]    [Pg.117]    [Pg.126]    [Pg.188]    [Pg.189]    [Pg.190]    [Pg.190]    [Pg.282]    [Pg.60]    [Pg.270]    [Pg.74]    [Pg.125]    [Pg.190]    [Pg.125]    [Pg.793]   
See also in sourсe #XX -- [ Pg.189 ]



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