Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Cane-Celmer-Westley hypothesis

McDonald and Towne [6] extended studies of Townsend and Basak, [7] and presented an alternative model to the Cane-Celmer-Westley hypothesis ryn-oxidative polycyclization. The Townsend-Basak-McDonald hypothesis for the biosynthesis of monensin A (3) is depicted in Scheme 2. [Pg.230]

Scheme I. The Cane-Celmer-Westley hypothesis for the biosynthesis of monensin A (3) (a) stereoselective epoxidation (b) polyepoxide cascade it is assumed that the OH group at C(26) is also introduced during the epoxidation step. Scheme I. The Cane-Celmer-Westley hypothesis for the biosynthesis of monensin A (3) (a) stereoselective epoxidation (b) polyepoxide cascade it is assumed that the OH group at C(26) is also introduced during the epoxidation step.
A fully satisfying answer to the question of the biosynthesis of polyether compounds such as monensin A (3) cannot be given from the results described here. However, it is clear that the new the Townsend-Basak-McDonald hypothesis has gained ground on the older Cane-Celmer-Westley hypothesis. A key experiment to test the Townsend-Basak-McDonald hypothesis will be the use of labeled (Z,Z,Z)-triens of type 4 in feeding experiments with Streptomyces cinnamonensis. [Pg.231]

See other pages where Cane-Celmer-Westley hypothesis is mentioned: [Pg.230]    [Pg.230]   
See also in sourсe #XX -- [ Pg.230 ]

See also in sourсe #XX -- [ Pg.162 , Pg.163 ]



SEARCH



© 2024 chempedia.info