Camphene hydrozirconation

With cyclic alkenes, fairly high diastereoselectivity can be achieved. Hydrozirconation of norbomene, followed by TBHP oxidation, gives the exo-alcohol in 95% yield, while the more complex bicyclics camphene (37) and P-pinene (38) give the mixtures shown in equations (39) and (40), respectively. TTie hafnium analog shows the opposite preference with P-pinene and does not react with camphene at all, attributed to significantly greater steric demand. Diastereoselectivity in cyclohexanols obtained by hydrozirconation of ketones has also been examined. ... 

---

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

---