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Calmodulin-stimulated dopaminergic

Effects of Dopaminergic Antagonists on Calmodulin-stimulated Phosphodiesterase Activity... [Pg.16]

Effects of dopaminergic antagonists on dopamine-stimulated cAMP accumulation, adenylate cyclase activity, and calmodulin-stimulated phosphodiesterase (PDE) activity in intact bovine parathyroid cells or cellular homogenates. Values for or IC50 are given as uM. NT, not tested. [Pg.17]

Figure 11.6. Schematic diagram of the possible sites of action of drugs that modify dopaminergic function in striatal and other non-mesocortical regions of the mammalian brain. PCM=protein 0-methyltransferase, which catalyses the transfer of methyl groups from S-adenosylmethionine to the calmodulin-dependent regulatory protein and may regulate calcium-calmodulin dependent transmitter synthesis and release. (—)=inhibition (+)=stimulation DA=dopamine. Sites of action of drugs are underlined. Figure 11.6. Schematic diagram of the possible sites of action of drugs that modify dopaminergic function in striatal and other non-mesocortical regions of the mammalian brain. PCM=protein 0-methyltransferase, which catalyses the transfer of methyl groups from S-adenosylmethionine to the calmodulin-dependent regulatory protein and may regulate calcium-calmodulin dependent transmitter synthesis and release. (—)=inhibition (+)=stimulation DA=dopamine. Sites of action of drugs are underlined.

See other pages where Calmodulin-stimulated dopaminergic is mentioned: [Pg.371]    [Pg.171]    [Pg.17]    [Pg.261]    [Pg.162]    [Pg.307]   


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