Polycarbophil calcium

Attapulgite adsorbs excess fluid in the stool with few adverse effects. Calcium polycarbophil is a hydrophilic polyacrylic resin that also works as an adsorbent, binding about 60 times its weight in water and leading to the formation of a gel that enhances stool formation. Neither attapulgite nor polycarbophil is systemically absorbed. Both products are effective in reducing fluid in the stool but can also adsorb nutrients and other medications. Their administration should be separated from other oral medications by 2 to 3 hours. Psyllium and methylcellulose products may also be used to reduce fluid in the stool and relieve chronic diarrhea. 

Calcium polycarbophil Adults 1000 mg 4 times daily or after each loose stool, not to exceed 12 tablets per day Children ages 6-12 500 mg 3 times daily Children ages 3-6 500 mg twice daily ... 

Hydrophilic substances such as calcium polycarbophil (FiberCon, Equalactin), methylceUulose (Citrucel), and various psyllium seed derivatives (Metamucil) are natural or synthetic fiber supplements that bind water and bile salts and may be useful in controlling diarrhea associated with the passing of excessively watery stools. 

The bulk-forming laxative group includes the hydrophilic substances described previously calcium polycarbophil FiberCon, Equalactin), methylcellulose Citrucel), and various psyllium seed derivatives Metamucil). All act by increasing the bulk of the feces, part of this action being due to their capacity to attract water and form a hydrogel. The increased volume of feces stretches the walls of the GI tract and stimulates peristalsis. Their action may not be evident for 2 to 3 days after starting treatment. Because their use results... 

Porter, and J. S. Fordtran. Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein. Gastroenterology 1993 104(4) 1007-1012. Colliopoulos, J. Psyllium-based laxative compositions. Patent-US-5,232, 699 1993 6 p. 

Empirical formula calcium polycarbophil is the calcium salt of polyacrylic acid crosslinked with divinyl glycol. 

CALCIUM POLYCARBOPHIL (Equalactin, Fiberall, FiberCon, Mitrolan)... 

Calcium polycarbophil, a hydrophilic agent that absorbs water (1 g p.o. q.i.d.), is used in the treatment of constipation. 

Calcium polycarbophil (FiberCon), methylcellulose (Citrucel), fiber granules (Perdiem), and psyllium hydrophihc mucilloid (Metamucil) are examples of bulk-forming laxatives. Patients with hypercalcemia should avoid calcium polycarbophil because of the calcium in the drug. Metamucil is a nondigestible and nonabsorbent substance that when mixed with water, becomes a viscous solution. There is no protein-binding or half-hfe for the dmg. It is excreted in the feces. There are no systemic effects. Nausea can occur with excessive use. The dry form can cause abdominal cramps. 

Kato R, Ueno K, Imano H, Kawai M, Kuwahara, Tsuchishita Y, Yonezawa E, Tanaka K. Impairment of ciprofloxacin absorption by calcium polycarbophil. 7 C/ / Pharmacol 2 2) 42, 806-11. 

Kato R, Ooi K, Hcura-Morii M, Tsuchishita Y, Hashimoto H, YoshiniuraH, Ueni i K, Kawai M, Tanaka K, Ueno K. Impairment of mycophenolate mofe absoption by calcium polycarbophil. J Clin Pharmacol (2002) 42,1275-80. 

Novatone. See Acetanisole Novawet G-3300. See Isopropylamine dodecylbenzenesulfonate Novazone AS. See Mixed diaryl-p-phenylenediamine Novei a 10-3. See Deceth-3 Novel II1214GC-2. See Laureth-2 Novel il 1412-7. See Laureth-7 Novel N3.0-1216CO. See C12-16 pareth-3 Novelose 240, Novelose 260. See Starch Novelose 330. See Maltodextrin Noveon AA-1. See Polycarbophil Noveon CA-1, Noveon CA-2. See Calcium polycarbophil Novocaine. See Procaine Novodur L3FR, Novodur M3FR, Novodur ... 

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