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Calcium channels overview

In this chapter, we provide a brief overview of voltage-gated calcium channel subtypes and function, with an emphasis on neuronal transmission. The structure and kinetics of calcium channels is an extensive field of study, and outstanding reviews have recently appeared [3,4]. This chapter is focused on the potential opportunities for small-molecule intervention in neuronal signaling via antagonism of voltage-gated calcium channel subtypes, with a brief review of the chemotypes that have been recently reported to modify channel function. [Pg.4]

Held PH, Yusuf S, Furberg CD. Calcium channel blockers in acute myocardial infarction and unstable angina an overview. BMJ 1989 299(6709) 1187-92. [Pg.606]

Figure 6.1. Overview of cellular calcium transport. Calcium enters the cell through voltage- or ligand-gated channels (left). It is extmded by ATP-driven pumps or by sodium antiport (right). Both the mitochondria and the endoplasmic reticulum serve as intracellular calcium stores. The cytosolic concentration is kept at -100 nM under resting conditions. CaM Calmodulin. Figure 6.1. Overview of cellular calcium transport. Calcium enters the cell through voltage- or ligand-gated channels (left). It is extmded by ATP-driven pumps or by sodium antiport (right). Both the mitochondria and the endoplasmic reticulum serve as intracellular calcium stores. The cytosolic concentration is kept at -100 nM under resting conditions. CaM Calmodulin.
See other pages where Calcium channels overview is mentioned: [Pg.263]    [Pg.341]    [Pg.7]    [Pg.173]    [Pg.479]    [Pg.358]    [Pg.149]    [Pg.477]    [Pg.422]    [Pg.130]    [Pg.111]    [Pg.108]    [Pg.294]   
See also in sourсe #XX -- [ Pg.401 , Pg.402 ]

See also in sourсe #XX -- [ Pg.203 , Pg.204 , Pg.205 , Pg.206 , Pg.227 , Pg.228 ]



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Calcium channels

Calcium overview

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