Calcium channels myocyte level

Li Rinzel, 1994). The latter reductions therefore yield a minimal model for Ca oscillations, like the earlier, two-pool minimal model considered below, which takes into account only CICR and not the inhibition of Ca " release at high levels of cytosolic Ca. A one-pool version of this model in which Ca and IP3 behave as co-agonists for Ca " release is presented in section 9.4. A model based on the bellshaped calcium dependence of the ryanodine-sensitive calcium channel was recently proposed for calcium dynamics in cardiac myocytes (Tang Othmer, 1994b). 

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