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Cacchi synthesis

The Cacchi synthesis and closely related indole syntheses involving the Pd-catalyzed cyclization/trapping of 2-aIkynylanilines have filled the organic literature, and three recent examples are shown in Scheme 3 (equations 1-3) [9-11]. Moreover, this chemistry has been applied to solid-phase synthesis (EUingboe [12]), 3-iodoindoles (Barluenga... [Pg.615]

The Cacchi synthesis of indoles via the Pd-catalyzed cyclization of 2-aIkynylaniUnes and subsequent functionalization has extended enormously the original Yamanaka-Sakamoto-Sonogashira and Larock reactions. For a review of these methods see Beller [41]. [Pg.615]

Cacchi synthesis (indole) 140 Chichibahin reaction 352 Chichibabin synthesis (indolizine) 153 Claisen synthesis (isoxazole) 188 Combes synthesis (quinoline) 399 Cook-Heilbron synthesis (thiazole) 206 Corey synthesis (oxirane) 22 Cornforth rearrangement 171 imino-Corey reaction 36... [Pg.630]

See other pages where Cacchi synthesis is mentioned: [Pg.274]    [Pg.368]    [Pg.144]    [Pg.561]    [Pg.396]    [Pg.789]    [Pg.230]    [Pg.534]    [Pg.381]    [Pg.728]    [Pg.238]    [Pg.270]    [Pg.373]    [Pg.1021]    [Pg.1155]    [Pg.528]    [Pg.615]    [Pg.131]    [Pg.164]    [Pg.528]    [Pg.140]    [Pg.191]    [Pg.534]   


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Cacchi indole synthesis

Palladium-Catalyzed Indole Ring Synthesis Cacchi

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