C-seco analogs

Various C-seco analogs have been prepared in addition to 4.2.2.6 described above. Thus treatment of 10-deacetylbaccatin III with cupric acetate gave the 10-oxo derivative as described previously 42), and treatment of this compound with sodium borohydride and ceric chloride gave a mixture of the lO-e/ /-10-deacetylbaccatin III and the D-seco product 4.2.2.9 182). In a later publication the taxol analogs 4.2.2.10-4.2.2.13 were prepared by standard methods from 4.2.2.9 183). 

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