C2H5+

Me2NCH2) C2H5)(Me)C-OOC Ph-HCI. Colourless crystalline powder with a bitter taste, m.p. 177-179"C. Prepared by the action of ethyl magnesium bromide on dimethyl-aminoaceione. It is a local anaesthetic, mainly used to produce spinal anaesthesia. 

The free radicals which have only a transient existence, like -CHa, C2H5 or OH, and are therefore usually met with only as intermediates in chemical reactions, can usually be prepared and studied directly only at low pressures of the order of 1 mm, when they may be transported from the place of preparation in a rapidly streaming inert gas without suffering... 

The C2H5 is a carbonium ion (cf. ammonium NH4) and reacts with the benzene ... 

QHe + C2H5" C,H5C2H5 + and then hydrogen chloride and aluminium chloride are formed ... 

In the flask was placed a solution of 0.44 mol of butyllithium in about 300 ml of hexane. To this solution were added, with coaling below -20°C, 800, 600 and 400 ml of dry diethyl ether (note 1) in the case of R = CH3, C2H5 and tert.-CuHj or Me3Si, respectively. Subsequently 0.46 mol of the alkyne [in the case of R = CH3, C2H5 a cooled (-30°C) solution in 50 ml of diethyl ether] was added in about 10 min, while keeping the temperature below -20 c. The suspension (in the... 

The compounds with R = CH3 and C2H5 were collected in a cooled receiver (0°C). 

CH3OCH2CECH + H0-CH2-N(C2H5)2 -----------> CH30-CH2C C-CH2N(C2H5)2... 

Vote 2. A large excess of R MgCl is required, as the subsequent metallation of the enyne is rapid. In the case of C2H5 the Grignard reagent was prepared from ethyl bromide. 

---