4- butyric acid hydrazide

Azidobutyric Acid, Ethyl Ester. See under Butyric Acid and Beil 2, 287,299 (126,130) Azidobutyric Acid Hydroxide, See under Butyric Acid Hydrazide and Beil 2, (126)... 

N-e-maleimidocaproic acid) hydrazide, EMGH 4-(4-N-maleimidophenyl) butyric acid hydrazide hydrochloride, MPBH N-(k-maleimidoundecanoic acid)hydrazide, KMUH succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate, SMCC (all from Pierce Biotechnology Inc., Rockford, IL). 

Introduction of R. Resin-hound thiosemicarhazide Resin 49, obtained as described above, was treated with a 0.14 m solution of bis(2-pyridyl)thiono-carbonate in DMF (5 mL, 0.7 mmol, 10 equiv.) and agitated for 1 h at rL The resulting resin was filtered off and washed consecutively with anhydrous DMF (2x5 mL), CH2CI2 (2x5 mL), and anhydrous THF (2x5 mL). This intermediate isothiocyanate resin was suspended in anhydrous DMF (5 mL), treated with butyric acid hydrazide (0.15 g, 1.5 mmol, 21.4 equiv.), and agitated overnight. The resin was then washed consecutively with DMF (2 x... 

CA Index Name 1-Pyrenebutanoic acid, hydrazide Other Names Pyrenebutyric acid hydrazide 1-Pyrenebutyric acid hydrazide PyrenebutyryUiydrazine l-PyrenebutyryUiydrazine Pyrene butanoic acid hydrazide 4-(l-Pyrene)butanoic acid hydrazide 4-(l-Pyrene)butyric acid hydrazide 4-(l-Pyrene)butyryl hydrazide PBH... 

Salts of tliiols (170) or of sulfinic acids (171) react like the alkoxides, giving 4-alkyltliio- or 4-alkylsulfono-substituted butyrates. Alkali cyanides give 4-cyanobutyrates (172), kydroxylamine gives a kydroxamic acid (173), and hydrazine a hydrazide (174). 

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