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4- butyrate esters protect alcohols

Seebach completed the first synthesis of optically active 9 as depicted in Scheme 4.2. ° Protected alcohol 10, available from an optically active p-hydroxy butyric ester, was alkylated with 2-lithio-1,3-dithiane. Deprotonation of this material followed by formylation with DMF then afforded 11. Chain extension to the unsaturated ester was accomplished via a Wittig condensation and deprotection to produce the monomeric unit 12 in 57% overall yield from 10. Double lactonization under Mitsunobu conditions (DEAD-PhjP) afforded a 60%... [Pg.103]

See other pages where 4- butyrate esters protect alcohols is mentioned: [Pg.96]    [Pg.580]    [Pg.109]    [Pg.181]    [Pg.310]    [Pg.141]    [Pg.46]    [Pg.453]    [Pg.162]   
See also in sourсe #XX -- [ Pg.113 ]

See also in sourсe #XX -- [ Pg.113 ]

See also in sourсe #XX -- [ Pg.268 ]



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4- butyrate esters

Alcohol Protection

Alcoholic esters

Butyric alcohol

Esters alcohol protection

Esters alcohols

Esters, protection

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