3- Butyn-l-yl trifluoromethanesulfonate

A. 3-Butyn-l-yl Trifluoromethanesulfonate. A 500-ml., three-necked flask is fitted with a mechanical stirrer, a pressure-equalizing dropping funnel, and a stopper. The system is flushed with nitrogen through a gas-inlet tube attached to the top of the funnel. To 150 ml. of dry methylene chloride (Note 1) in the flask is added 75 g. (0.27 mole) of trifluoromethanesulfonic acid anhydride (Note 2), and the solution is cooled to —40°. After addition of 14.5 g. (0.14mole) of finely powdered anhydrous sodium carbonate (Note 3), 15 g. (0.21 mole) of 3-butyn-l-ol (Note 4) is added dropwise over a 20-minute period to the well-stirred reaction mixture maintained at —40° to —55°. Stirring is continued at —30° for 2 hours and then at 0° for another hour, and finally the... 

Synthesis of cyclobutanone (4, 533). The synthesis of cyclobutanone from 3-butyn-l-yl trifluoromethanesulfonate has been pubhshed. ... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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