3- Butyl hydroxy urea

Butylated hydroxyanisole. See BHA Butylated hydroxymethyl phenol. See4-Hydroxy methyl -2,6-d i-t-butyl phenol Butylated hydroxytoluene. See BHT Butylated melamine-formaldehyde resin. See Melamine-formaldehyde resin, butylated Butylated phenol-formaldehyde resin. See Butylphenol formaldehyde Butylated polyoxymethylene urea (INCI). See Urea-formaldehyde resin, butylated Butylated polyvinylpyrrolidone. See Butylated PVP... 

OH-DPAT = 8-Hydroxy-2-(di-n-propylamine)tetralin CP93129 = 5-Hydroxy-3(4-l,2,5,6-tetrahydropyridyl)-4-azaindole LY334370 = 5-(4-fluorobenzoyl)amino-3-(l-methylpiperidin-4-yl)-l -indole fumarate SB204741 = A/-(l-methyl-5-indolyl)-/V -(3-methyl-5-isothiazolyl)urea WAY100635 = N-tert-Butyl 3-4-(2-methoxyphenyl)piperazin-l-yl-2-phenylpropanamide. 

Open chain esters, amides and alkyl-ureas may also be bitter (Table XIX). The c- bi-values depend on the hydrophobicity of the side chains. Primary, secondary and tertiary amines are bitter (Table XX). The c-tbi-values of compounds with equal side chains decrease in the same order. But with the i-butyl-residue, c j reaches a minimum with the secondary amine. Possibly there are problems with three somewhat bulky residues at the receptor site, ctbi increases with hydrophilic substituents in the side chain, as is shown with the ethyl and hydroxy-ethyl compounds. 

The reaction of -halo carbonyl compounds with primary amides is appropriate for oxazoles containing one or more aryl groups . Ureas form 2-aminooxazoles. Formamide can be used resulting in a free 2-position in the oxazole. A convenient synthesis of 5-substituted-4-cyanooxazoles 223 is based on the condensation of -hydroxy—cyanoenamines 222 with trimethyl orthoformate (Scheme 109). The cyanoenamine intermediates 222 are derived from Lewis acid-catalyzed Passerini reactions between /-butyl isonitrile and aldehydes <2002S1969>. 

Dimethyl-5-ethoxycarbonyl-E16c, 122 (En-azid/Ringschl.) Pyrido[3,4-d pyridazin 1,4-Diethoxy-E9c, 68 (Cl - OR) Pyrido[2,3-d(pyrimidin 1 -Butyl-4-hydroxy-2-oxo-l,2-dihydro- E9c, 97 (2-NH R — 3-COOH—py + Urea)... 

The application of additives was investigated in order to suppress or diminish side reactions (A-acyl urea formation and racemization). Al-Hydroxysuccinimide (HOSu), 1-hydroxybenzotriazole (HoBt), and ethyl l-hydroxy-lH-l,2,3-triazole-4-carboxylate are potential additives in the DCC-based coupling synthesis. Solid-phase peptide synthesis (SPPS) is a variant of the linear (stepwise) coupling of amino acids in the C N direction using two major protection groups Boc/Bzl (iert-butoxycarbonyl/benzyl) and Fmoc/tBu (/9-fluorenylmethoxycarbonyl/ieri-butyl). The synthetic scheme for peptides on a polymer (Atherton and Sheppard, 1989 Fields, 1997) is illustrated in Figure 8.1. 

Trimethylpentanediol/isophthalic acid/trimellitic anhydride copolymer Trioctyidodecyl citrate 1,1,3-Trls (2-methyl-4-hydroxy-5-t-butylphenyl) butane Tromethamine acrylates/acrylonitrogens copolymer Urea-formaldehyde resin, butylated... 

Even after prolonged stoving, however, the hardened resins still retain a high proportion of butoxy groups. When butylated urea-formaldehyde resin/alkyd resin blends are stoved, there is the further possibility of ether interchange between the butoxy groups and free hydroxy groups in the alkyd resin ... 

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