Butene diol

The reaction of a halide with 2-butene-1,4-diol (104) affords the aldehyde 105, which is converted into the 4-substituted 2-hydroxytetrahydrofuran 106, and oxidized to the 3-aryl-7-butyrolactone 107[94], Asymmetric arylation of the cyclic acetal 108 with phenyl triflate[95] using Pd-BINAP afforded 109, which was converted into the 3-phenyllactone 110 in 72% ee[96]. Addition of a molecular sieve (MS3A) shows a favorable effect on this arylation. The reaction of the 3-siloxycyclopentene 111 with an alkenyl iodide affords the. silyl... 

C4Hg0j 2-Butene-1,4-diol (Z) C4H]q04S ESryl sulphate... 

EPOXYBUTANE METHYL ETHYL KETONE ETHYL VINYL ETHER TETRAHYDROFURAN cis-2-BUTENE-1,4-DIOL trans-2-BUTENE-1,4-DIOL ISOBUTYRIC ACID n-BUTYRIC ACID... 

In this work we extend our study to the hydrogenation and isomerization of a series of a,p-unsaturated alcohols, such as 2-propen-l-ol (A2), (E -2-buten-l-ol (EB2), (" -2-penten-l-ol (ZP2), (E -2-penten-l-ol (EP2), (" -2-hexen-l-ol (ZH2), (E -2-hexen-l-ol (EH2), carried out in the presence of RhCl(PPh3)3, with and without triethylamine (NEts), at 303 K, using ethanol as solvent. The major targets of our research are to investigate the influence of the unsaturated alcohol structure on the product distribution and to verify the possibility of extending the results, previously obtained with (" -2-butene-1,4-diol, to other analogous substrates. 

Charette and coworkers have shown that the diastereoselective cyclopropanation of chiral allylic alcohols with gem-dizinc carbenoids proceeds with high diastereocontrol for protected 2-butene-1,4-diol derivatives (equation 63). The minimization of the A-1,3 strain and the formation of a zinc chelate in the product is believed to be responsible for... 

Dehydration of diols to cyclic ethers. The reagent dehydrates a variety of diols to cyclic ethers with formation of triphenylphosphine oxide as the co-product. Yields of cyclic ethers are high from 1,2-, 1,4- and 1,5-diols. Although (Z)-2-butene-1,4-diol is converted into 2,5-dihydrofuran in 95% yield, the (E)-isomer is converted in 35-40% yield into 3,4-epoxy-l-butene.1... 

Metal loading influence on catalytic activity and selectivity, S, in the catalytic hydrogenation of 2-8utyne-1,4-diol, rT, and cis-2-Butene-1,4-diol, rD,... 

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