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1.4- Butanediol Busulfan

The chloro derivative 2, X = Cl was the most active and was selected for clinical trials. The diester of 1,4-butanediol (busulfan) 3 is an alkylating agent, specific for the granulocyte series and used in therapy of chronic myeloid leukemia19. [Pg.768]

Butanediol dimediylsulfonate (busulfan) Cadmium and cadmium compounds Chlorambucil... [Pg.169]

It is prepared by the interaetion of 1,4-butanediol with two moles of methane sulphonyl chloride in the presence of pyridine, when the final product obtained is recrystallised either from acetone or alcohol. Busulfan is broadly used in the treatment of granulocytic leukemia. [Pg.807]

Butanediol dimethylsulfo-nate Busulfan C6H44O0S2 55-98-1 246.301 cry 116 i H2O si EtOH, ace... [Pg.219]

See other pages where 1.4- Butanediol Busulfan is mentioned: [Pg.1618]    [Pg.1618]    [Pg.1618]    [Pg.1618]    [Pg.302]    [Pg.449]    [Pg.302]    [Pg.547]    [Pg.211]    [Pg.212]    [Pg.231]    [Pg.240]    [Pg.2516]   


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1 : 4-Butanediol

1,4-butanediole

Busulfan

Butanediols

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