Rifampicin Bunazosin

Rifampicin markedly reduces bunazosin serum levels. [Pg.88]

In 15 healthy subjects a 7-day course of rifampicin 600 mg daily reduced the mean maximum serum levels of bunazosin 6 mg daily by 82% (from 11.6 to 2.1 nanograms/mL). The bunazosin AUC was reduced by more... [Pg.88]

The evidence seems to be limited to this study, but anticipate the need to raise the bunazosin dosage if rifampicin is added. Information about other alpha blockers does not seem to be available. [Pg.89]

Al-Hamdan Y, Otto U, Kirch W. Interaction of rifampicin with bunazosin, an alphai-adreno-ceptor antagonist. J Clin Pharmacol (1993) 33,998. [Pg.89]

Nokhodian A, Halabi A, Ebert U, Al-Hamdan Y, Kirch W. Interaction of rifampicin widi bunazosin, an ai-adrenoceptor antagonist, in healthy volunteers. Drug Invest 993>) 6, 362-4. [Pg.89]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...