Thermal properties, brain tissues

Table B5.5 Thermal properties of normal, unperfused human brain tissue...

Gd, Gd, and Hf. The properties of B are favorable, and boron compounds have been tested clinically (for over 20 years in Japan) for the treatment of melanomas, bone marrow and malignant brain tumors (82). The isotope B undergoes fission on bombardment with thermal or epithermal neutrons, giving rise to a particles that are destructive to local tissue (within 10 p,m) ... 

The distribution of soluble arylsulphatases in human tissues has been examined via ion-exchange chromatography. All tissues contained arylsulphatase A and B. In addition, brain singularly contained significant quantities of a minor anionic form (Bm) only trace amounts of Bm were found in liver, kidney, testis, and placenta. Arylsulphatases B and Bm had equal activity towards methylumbelliferyl sulphate, nitrocatechol sulphate, and UDP-2-acetamido-2-deoxy-D-galactose 4-sulphate, but both forms were inactive toward the arylsulphatase A substrates cerebroside sulphate and L-ascorbic acid 2-sulphate. The physicochemical properties of arylsulphatases B and Bm differed with respect to thermal stability, ionicity, and behaviour on polyacrylamide gel electrophoresis and isoelectric focusing. 

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