Bradykinin-generating cascade

Bradykinin, which has been studied extensively in inflammation, infection and in cancer is an important mediator of the FPR effect. It is well known that bradykinin mediates pain and increases vascular permeability and even angiogenesis We reported previously that the bradykinin-generating cascade is activated in the tumor compartment and that bradykinin may be involved in malignant ascitic and pleural fluid accumulation ... 

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