Br0nsted acid chiral

As a stronger Br0nsted acid, chiral binaphthol-based phosphoric acid 8 and /V-triflyl phosphoramide 9 were recently introduced to the FCA reaction of enones. Reports by a few groups on the alkylations of indoles showed that simple enones were still challenging substrates, and modest ee values were recorded with a few examples over 90% ee (Scheme 9.8) [23]. However, excellent enantioselectivities were achieved in the intramolecular C3 and N1 alkylations of indole by You and co-workers (Scheme 9.9) [24]. Noteworthy, chiral oxazaborolidinone and... 

Br0nsted Acid/Chiral (Thio)urea Combination... 

Br0nsted Acids Chiral Phosphoric Acid Catalysts in Asymmetric Synthesis... 

Br0nsted Acids Chiral (Thio)urea Derivatives... 

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