Bowes melanoma cell line

We have identified a known posttranslational modification, hydroxylysine, in unexpected places. This modification is only partial, typically 5-25%, at one site only in tPA (at Lys /), rCD4 (at Lys ) and rCD4-IgG (at Lys ). All of the observed Hyl sites were foxmd in Xaa-Hyl-Gly sequences, as is the case for the known Hyl sites in collagens. The modification appears to be cell line-independent, as it was found in tPA from Bowes melanoma cells as well as rtPA from transfected CHO and 293 cells. 

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