Bound water in proteins

Hasl, G. and Pauly, H. 1971. Calorimetric properties of the bound water in protein solutions. Biophysik 7, 283-294 (German). 

The intracellular water is represented by two or three relaxation processes. There is no reason to suppose that the faster components represent "bound" water, firstly because their magnitude is too small to be equated with the 0.5 to 1 g/g protein of water normally associated with protein hydration, and secondly, because exchange between free and bound water in protein systems... 

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