Boonss Latent-Active Glycosylation

The techniques of Hindsgaul s random glyco-sylation. Boons s latent-active glycosylation and Kahne s solid phase methodology now make the synthesis of di- and trisaccharide combinatorial libraries a feasible process. Also, a colorimetric... 

Boons G-J, Isles S. Vinyl glycosides in oligosaccharide synthesis (part 1) a new latent-active glycosylation strategy. Tetrahedron Lett. 1994 35 3593-3596. 

Boons, G J, Heskamp, B, Hout, F, Vinyl glycosides in ohgosaccharide synthesis a strategy for the preparation of trisaccharide hbraries based on latent-active glycosylations, Angew. Chem. Int. Ed. Engl, 35, 2845-2847, 1996. 

This latent-active glycosylation strategy was also applied by Boons to the synthesis of libraries of both linear [31] and branched trisaccharides [32]. 

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