Bone SPARC protein

Bone SPARC protein (osteonectin) Not bone-specific. 

A second category of NCPs with Ca-binding properties is classified as mineraUzed tissue specific, since they are found in all the calcified connective tissues, namely, dentin, bone, and cementum. These proteins include osteocalcin (OC) and bone sialoprotein (BSP). A serine-rich phosphoprotein called dentin matrix protein 1 (Dmp-1), whose expression was first described as being restricted to odontoblasts [5], was later shown to be expressed by osteoblasts and cementoblasts [6]. Other NCPs include osteopontin and osteonectin [secreted protein acidic and rich in cysteine (SPARC)]. The fourth category of dentin NCPs is not expressed in odontoblasts but is primarily synthesized in the liver and released... 

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