Bitter flavone neohesperidosides

Figure 4. Minor structural changes to the aglycone portion of the molecule can destroy bitterness. Adding a single double bond between Carbons 2 and 3 will convert bitter flavanone neohesperidosides to tasteless flavone neohesperidosides.

Both directly and indirectly, flavonoid composition affects the quality of individual citrus cultivars and hybrids. Some cultivars, such as the sour orange, are directly affected by the presence of bitter neohesperidosides to the point they are unpalatable. The quality of other cultivars may be indirectly affected due to the presence of bitterness suppressing flavone neohesperidosides. Certain hybrids, such as the K early, also contain bitter flavanone glycosides at levels which reduce its acceptability. Therefore, the knowledge of the relative type and... 

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