Bis monomers

Righetti and CagUo [315] have also found that Bis reacts faster than acrylamide and that this leads to the formation of nonhomogeneous regions in the gel. At the critical gel point they found 50% of the acrylamide monomer and 80% of the Bis monomer had reacted. The reaction was found to continue beyond the gel point, with an eventual 99%... 

Figure 44 Proposed formation mechanism of polythiophene/protein wire bundles (a) structural image of polythiophene with an all trans backbone configuration (left). Structure of BI monomer (PDB file lAPH) with a tyrosine side chain shown for comparison (right), (b) Proposed interaction between a partially unfolded BI monomer (gray) and two polythiophenes (green), (c) Transmission electron microscopy of the wires after incubation for 6h at 65 °C and proposed structure, (d) Left Two fiuorescence micrographs of the corresponding poly thiophenes shown on the right (scale bar 20 pm). (Reproduced with permission from Ref. 78. Wiley-VCH, 2005.)...

The convergent or "arm-first method This consists first in the synthesis of arms by a living/ controlled polymerization. The latter are finally linked to each other by adding a multifunctional agent to the polymerization system. Addition of a small amount of a bis-monomer... 

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