Bis 3-benzoylquinoxalin-2-on-l-yl alkanes

Compound 163a was obtained as a mixture of two diastereomers (ca. 1 1), which were separated and characterized separately (Mamedov et al. 2009b). Presumably these diastereomers (conformers) are due to the different syn and anti) mutual orientation of the tricyclic systems. 

The formation of imidazoquinoxalines apparently proceeds through the tautomeric form D formed at the first stage of the reaction of the bases of Schiff C in which nucleophilic attack of atom N(4) on the imine atom of carbon occurs with the closure of the imidazoline cycle the aromatization of which when exposed to the DMSO or oxygen of the air leads to the imidazo[l,5-a]quinoxalin-4-one derivatives (Fig. 5.10). 

The imidazoannulation of 3-benzoylquinoxalin-2-ones has been widely studied on various ketones of quinoxalines in their reactions with compounds containing an aminomethyl moiety (benzylamine picolylamine, m-xylylenediamine), that allowed the creation a library of imidazo[l,5-a]quinoxalines with substituents at different positions (Mamedov et al. 2004a, 2009b, 2008a, b Kalinin et al. 2013). 

In a continuation of their work, the authors (Mamedov et al. 2009a, 2013a, b Kalinin et al. 2009, 2013 Yanilkin et al. 2009) toward the development of methods 

The pyridinyl substituent in position 1 of l,10-bis- 3-phenyl-l-(pyridin-3-yl) imidazo[l,5-a]quinoxalin-4-on-5-yl decane 170, which then would be subjected to alkylation with alkyl dihalides with the formation of pyridinium salts, opens the 

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