Biomimetic adhesion strength

Figure 10.4 Diversity of chemistiy structures utilized to create biomimetic adhesive polymers. Catechol side chain (A) modification alters its interfacial binding strength and reactivity. Substitution can be achieved by replacing -H at the para position with chloro-(B), nitro- (C) and hydrojyl (D) groups or a hydro)yl group at the meta position (E). The benzene ring can be substituted with a pyridine group (F). Linking the catechol with a polymer can be achieved via reaction of the amino acid (G), acid (H), or amine (I) groups. Catechol modified with a bromide propionamide Initiator to initiate polymerization (J) or functionalized with polymerizable methacrylamide (K), vinyl (L), and M-carboxyanhydride (NCA, M) groups.

At present, computational fluid dynamics methods are finding many new and diverse applications in bioengineering and biomimetics. For example, CFD techniques can be used to predict (1) velocity and stress distribution maps in complex reactor performance studies as well as in vascular and bronchial models (2) strength of adhesion and dynamics of detachment for mammalian cells (3) transport properties for nonhomogeneous materials and nonideal interfaces (4) multicomponent diffusion rates using the Maxwell-Stefan transport model, as opposed to the limited traditional Fickian approach. 

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