Biometal-organic chemistry

It is necessary now to classify the metals with regard to their function in biological systems metals as cofactors of proteins, metalloen2ymes, communicative functions of metals, interaction of metal ions with polynucleotides, biometal-organic chemistry (e.g. metals in medicine). 

A bridge between natural and artificial macromolecular metal complexes is the interaction of metal ions/complexes with peptides/proteins [70], nucleic acids/DNA [71,72], enzymes [73], steroids [74], carbohydrates [75]. Biometal-organic chemistry concentrates on such complexes [15], The reason for the increasing interest in this field lays in medical applications of metal complexes [16,76] (cancer, photodynamic therapy of cancer -immuno-assays, fluorescence markers, enantioselective catalysis, template orientated synthesis of peptides) as exemplarily shown below. 

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