Biomedical interest

Schuerch, C. The Chemical Synthesis and Properties of Polysaccharides of Biomedical Interest. Vol. 10, pp. 173-194. 

Ring-opening polymerization has played an important role in systematic approaches to the chemical synthesis of polysaccharides and the clarification of their biomedically interesting characteristics in relation to their own molecular structures. The early... 

Many compounds of biomedical interest, both of endogenous and exogenous origin, are heterocyclic in structure. Many of these compounds are electroactive at potentials useful for LCEC analysis. Methods for the determination of both ascorbic acid and uric acid were developed in the early days of LCEC. The important enzyme... 

Several heterocycles of biomedical interest are reducible. Among these the K vitamins and the pterins have been determined by LCEC. Some heterocyclic... 

Stability of Complexes of Imidazole with Metal Ions of Biological and Biomedical Interest ... 

These materials are of potential biomedical interest and their... 

Several eco-friendly approaches to vinyl-/i-lactams (219-221) bearing a vinyl substituent at various positions on the ring (Scheme 9.71) have recently been described by Manhas [122]. Vinyl-/i-lactams are efficient synthons for a variety of compounds of biomedical interest, e. g. isocephalosporins, carbapenem intermediates and pyrrolidine alkaloids. MORE chemistry techniques allow highly accelerated syntheses using limited amounts of solvent and with efficient stereocontrol, thus achieving high atom economy . 

HPLC is limited by sample volatility or thermal stability. It is also ideally suited for the separation of macromolecules and ionic species of biomedical interest, labile natural products, and a wide variety of other high molecular weight and/or less stable compounds (see Section 15.12). 

The radioactive isotope 18F has been used for the preparation of substituted compounds of potential biomedical interest.206,207 Among... 

A number of excellent references are available for classical techniques, including those by Kowalski et al. [7, 8], Kramer [9], Brereton [10], compilations [11, 12], and series of periodic reviews [13]. There are two somewhat related problems in chemometrics that are relevant to spectral data. The first is to predict molecular identifications in mixtures from a spectrum and the second is to predict a class or label for a spectrum. While regression techniques work well for molecular identifications, problems of biomedical interest often involve stochastically varying compositions and spatial distributions of... 

C. Schuerch, Chemical synthesis and properties of polysaccharides of biomedical interest, Fortschr. Hochpolym.-Forsch., 10 (1972) 173—194. 

---