Biological Roles for Bacterial Sialidases

Solovev et aL (1972) have shown that noncholera vibrios have far lower sialidase activity than cholera vibrios and suggested that sialidase activity be used as an aid in Vibrio taxonomy. Thomas (1970) has proposed that sialidase might be the toxic factor elaborated by some mycoplasmas. Muller (1971, 7) has called attention to the similar 

Source of sialidase Substrate Effect on substrate Reference 

Vibrio choleme and A/Lee and swine S15 influenza viruses Erythrocytes Release of heterogenetic mononucleosis receptor Springer and Rapaport, 1957 

Vibrio cholerae Erythrocytes No correlation with hemolysis Yachnin and Gardner, 1961 

Asian influenza virus Orosomucoid Increased antigenicity Athineos a/., 1962 

---