Biological exposure index

Threshold Timit Values and Biological Exposure Indices American Conference of Governmental and Industrial Hygienists, Cincinnati, Ohio, 1989, p. 124. 

Documentation of the Threshold IJmit Values and Biological Exposure Indices, American Conference of Governmental Industrial Hygienists (ACGIH), 5th... 

Threshold Eimit Valuesfor Chemical Substances and Physical Agents and Biological Exposure Indices, ACGIH, Cincinnati, Ohio, 1991. 

Chemical determinant Sampling time Biological exposure indices Notation... 

American Conference of Governmental Industrial Hygienists. Threshold limit values for chemical substances and physical agents and biological exposure indices. ACGIH, Cincinnati, OH. 1999. 

Biological exposure indices (BEI) published by the ACGIH are given in Table 4.35. BEIs represent the levels of determinant which are most likely to be observed in specimens collected from a healthy worker who has been exposed to chemicals to the same extent as a worker with inhalation exposure to the TLV. Due to biological variability it is possible for an individual s measurements to exceed the BEI without incurring increased health risk. If, however, levels in specimens obtained from a worker on different occasions persistently exceed the BEI, or if the majority of levels in specimens obtained from a group of workers at the same workplace exceed the BEI, the cause of the excessive values must be investigated and proper action taken to reduce the exposure. 

It is advisable to consult the specific documentation published in the Documentation of Threshold Limit Values and Biological Exposure Indices. 

There are three biological exposure indices (BEls) for exposure to trichloroethylene at the ACGIH threshold limit value time-weighted average (TLV-TWA) of 50 ppm (ACGIH 1996). When measured at the end of a 40-hour workweek, TCA in urine is approximately 100 mg/g creatinine when measured at the end of an 8-hour shift at the end of a workweek TCA and trichloroethanol in urine is approximately 300 mg/g creatinine, and free trichloroethanol in blood is approximately 4 mg/L. 

ACGIH maintains annual editions of the TLVs and BEIs which are used worldwide as a guide for evaluation and control of workplace exposures to chemical substances and physical agents. Threshold Limit Value (TLV ) occupational exposure guidelines are recommended for more than 700 chemical substances and physical agents. There are more than 50 Biological Exposure Indices (BEIs ) that cover more than 80 chemical substances. 

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