Bioindicators fluorescence

Roshchina V.V. (2003). Autofluorescence of plant secreting cells as a biosensor and bioindicator reaction. Journal of Fluorescence 13 403-420. 

As noted above, sophisticated techniques are available for the analysis of mutations at the gene and chromosomal level. Such analysis can be used to define the mechanisms of formation of specific human tumors. In addition, it can be used for the development of informative bioindicators of a tumor response. These include ligation-based PCR technique and fluorescence in situ hybridization (FISH) that can be used in conjunction with clones that cover limited genomic regions to identify specific chromosomal breakpoints (Preston, 2005a). 

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