Bioimaging in vitro

Cancer cell cultures (HeLa and NIH-3 T3) impregnated with 0.1 g/L meso-PSi nanoparticles and exposed to 60 J/cm white light exhibited 45 % cell death, while controls containing no nanoparticles showed 10 % and 25 % cell death for HeLa and NIH-3 T3 lines, respectively. The dark control experiment yields <10% cytotoxicity for either cell type (Xiao et al. 2011). Micro-PSi nanoparticles were found to penetrate into cancer cells, resulting in 70 % cell death after illumination (Osminkina et al. 2011). Micro-PSi nanoparticles were also examined as SO photosensitizers and photoluminescent labels in bioimaging in vitro, and then they were proposed for application in cancer theranostics (therapy and diagnostics) (Osminkina et al. 2012). 

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