Biochemical and Miscellaneous

Biochemical and Miscellaneous.—3-Methyl-2-benzothiazolone hydrazone is incorporated quantitatively into the anticodon loop of t-RNA from yeast. Reaction occurs by Schiff s base formation with the ribose aldehyde group remaining after excision of the base Y from the nucleotide. The reaction provides a method of chemically modifying the natural polymer, with retention of its biochemical activity.  

N-Methylbenzothiazolone hydrazone hydrochloride (MBTH) is suitable for characterizing steroids such as 17-hy oxy-3,20-dioxopregn-4-en-21-al as osazones. N-Methylbenzothiazolium and naphtho[2,l-d]thiazolium salts (121) and (122) and certain dimers, e.g. (123), promote catalytically the acyloin condensation of benzaldehyde to benzoin.  

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