Heterocycles binuclear, formation

Insertion of carbon monoxide followed by reductive coupling is an old reaction that continues to be studied and developed. Examples of this reaction are the carbonylation of nickel dialkyl complexes to give ketones, " alkyl-alkoxides to yield esters, and alkyl-amides to give organic amides (Equation (79)). The carbonylation of the binuclear complex 145 leads to the formation of an isoquinolone ring with the elimination of one of the two Ni atoms, but no GO insertion occurs at the second metal moiety. Hydrolytic cleavage of the remaining Ni-G bond provides the free heterocyclic base (Scheme 45). ... 

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