Binding hydrogen bond

DeChancie, J., Houk, K. N. The origins of femtomolar protein-ligand binding hydrogen-bond cooperativity and desolvation energetics in the biotin-(strept)avidin binding site. J. Am. Chem. Soc. 2007, 129, 5419-5429. 

Water absorption and binding Hydrogen-bonding of water, entrapment of water, no drip Meats, sausages, breads, cakes F,C... 

In this chapter, we will show how the concept of template-directed organic synthesis has expanded so that now metal-ligand binding, hydrogen bonding, n-n interactions, and covalent bonding can all be exploited to allow the synthesis of molecules with a remarkable degree of control. Several detailed reviews of molecular templates have been published [14-20]. This chapter explores the definition and classification of molecular templates and discusses how their performance can be quantified and optimized. 

Backbone folding in disubstituted triazoles and oligoindoles is due to a combination of solvophobic interactions, halide binding, hydrogen bonding, and aromatic stacking interactions (Figure 9.5). 

Fig. 7. Snapshots of rupture taken (A) at the start of the simulation (zcant = 0), (li) at ZcB.nl = 2.8 A, (C) at Zcnm = 4.1 A, (D) at Zcnm = 7.1 A, and (E) at Zcant = 10.5 A. The biotin molecule is drawn as a ball-and-stick model within the binding )ocket (lines). The bold dashed lines show hydrogen bonds, the dotted lines show selected water bridges.

A fuzzier atom type participating in these descriptors has been defined that is pharmacologically relevant - the physicochemical type at near-neutral pH [24], which is one of the following seven binding property classes 1 = cation 2 = anion 3 = neutral hydrogen-bond donor 4 = neutral H-bond acceptor ... 

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